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  • Paul G Thomas
    Paul G Thomas
    @PGTimmune
    Department of Immunology, St. Jude Children's Research Hospital
    Followers1K
    Following1K
    Tweets908
  • Science Immunology
    @SciImmunology
    4 days ago
    Two new studies that identified lung T resident helper cells, lay "a foundation for building our understanding of their role in mediating local #immunity after #viral infection," say Stefan Schattgen, @PGTimmune at @StJudeResearch: https://t.co/uZ3P7SeWbZ https://t.co/OLHNs5GDH5
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  • Paul G Thomas
    @PGTimmune
    10 days ago
    Beautiful new work on T resident helper cells in the lung--back to back, exhaustive papers. https://t.co/I5gvT3CalQ
    Jie Sun
    @Jie_Immunology
    10 days ago
    Happy our new paper is out: https://t.co/JBXtLWgMZJ. We show TRH cells coordinate mucosal CD8 and B cell memory development. See accompanying one from great @ImmunologyKing. Thx the insightful focus commentary from @PGTimmune
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    Tissue-resident CD4+ T helper cells assist the development of protective respiratory B and CD8+ T...

    Memory T cells take up residence in the lung after respiratory virus infection to facilitate rapid and localized immune responses during reinfection. Two studies in this week’s issue identify a...

    immunology.sciencemag.org
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  • Ali Ellebedy
    @TheBcellArtist
    18 days ago
    Does SARS-CoV-2 infection establish a long-lived bone marrow plasma cell compartment? We addressed this question by sampling the bone marrow of 18 patients 7-8 months after experiencing mild SARS-CoV-2 infection (pre-print). https://t.co/OkoSw6M8cB Happy new year!!
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    SARS-CoV-2 infection induces long-lived bone marrow plasma cells in humans

    Infection or vaccination induces a population of long-lived bone marrow plasma cells (BMPCs) that are a persistent and essential source of protective antibodies1–5. Whether this population is induced...

    www.researchsquare.com
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  • Prof Francois Balloux
    @BallouxFrancois
    22 days ago
    New study following 12,541 healthcare workers for #COVID19 re-infection over 31 weeks published in NEJM. Natural immunisation held up well over the 6 months of the study, with only two cases of asymptomatic reinfections observed. https://t.co/nlDg79Zszt https://t.co/LXMD2R3bq1
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  • Paul G Thomas
    @PGTimmune
    22 days ago
    The wait is over! The day has come! The time is now! The best holiday present you can imagine...tcrdist3!!!! https://t.co/qHjEkslO4K
    Andrew Fiore-Gartland
    @agartland
    22 days ago
    Excited to share our #SARS_CoV_2 #TCR repertoire preprint! A framework for biomarker discovery w/ antigen-enriched TCR data w/ app to #sarscov2. #tcrdist3+#immuneRACE=TCR "meta-clonotypes" https://t.co/c850DiEp8b Thanks @PGTimmune @sschattgen @Liel_Cohen_ @aanaishe @jeremycfd https://t.co/N0ASIrtBwS
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  • BlishLab
    @blish_lab
    a month ago
    Very happy to share our latest efforts to understand protective vs. pathogenic immune responses to #COVID19. https://t.co/00mAzEMfcf This was a massive collaborative effort . Thanks @wilk_aaronj and @m_janelee and....
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    Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in...

    Our understanding of protective vs. pathologic immune responses to SARS-CoV-2, the virus that causes Coronavirus disease 2019 (COVID-19), is limited by inadequate profiling of patients at the...

    www.biorxiv.org
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  • St. Jude Research
    @StJudeResearch
    a month ago
    As 2020 Nobel Prizes are given today, we mark the 24th anniversary of St. Jude emeritus faculty member @ProfPCDoherty receiving the @NobelPrize in Physiology or Medicine with Dr. Rolf Zinkernagel. Watch Dr. Doherty discuss the day in 1996. https://t.co/qRzIKYFZoi #NobelPrizeDay https://t.co/1E2D3FoOLl
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  • St. Jude Research
    @StJudeResearch
    a month ago
    What should we expect during this flu season? Watch an in-depth discussion with our infectious disease experts Drs. Robert Webster and Richard Webby as they dispel myths and talk about COVID-19 and influenza. https://t.co/EhRGu8DCD2 #FightFlu https://t.co/z5TcC90dBx
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  • Dr. Josephine Giles
    @facts___matter
    a month ago
    Looking forward to presenting at The Mark Foundation symposium! https://t.co/pb7w0hwRbo
    The Mark Foundation
    @TheMarkFdn
    a month ago
    On December 16 from 1-3 PM ET, we'll be holding a virtual symposium on Understanding and Overcoming Therapeutic Resistance, with speakers including @LucyJLXie, @shengfcai, and @facts___matter. Learn more and RSVP here to join us! https://t.co/4qSeqkxmDa
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  • Florian Krammer
    @florian_krammer
    a month ago
    1) Finally this it out. It took a few years of my life to get this into clinical trials (with the help of many others). A first step towards the clinical development of universal influenza virus vaccines. With Adolfo Garcia-Sastre, Peter Palese. https://t.co/J0LxSaRP5D
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    A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and...

    New influenza virus vaccines tested in humans elicit broadly cross-reactive antibodies that bind the stalk of the viral hemagglutinin protein and may serve as templates to design a universal influe...

    www.nature.com
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  • BlishLab
    @blish_lab
    2 months ago
    We are looking for motivated scientists to join our team! Learn about host-pathogen interactions across a range of pathogens, including SARS-CoV-2, HIV, influenza, and tuberculosis. https://t.co/YDDOHJO9m0. Please direct questions to our awesome lab manager @r_thanmayi
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    Life Science Research Professional in School of Medicine, Stanford, California, United States

    Stanford University Department of Medicine, Division of Infectious Diseases is seeking a Life Science Research Professional 1 to perform basic...

    careersearch.stanford.edu
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  • 💮Nicole La Gruta
    @NicoleLaGruta1
    2 months ago
    A lovely review on virtual memory T cells, including their confusing nomenclature & conflation with conventional memory populations, by my very talented students and postdoc @AngelaSciences, Dan Thiele & @TabiHussain. https://t.co/tCcfAJ6ZTP
    GRAS Lab
    @GrasLab
    2 months ago
    Fantastic new review with a great title: "Hiding in Plain Sight: Virtually Unrecognizable Memory Phenotype CD8+ T cells" https://t.co/mB9mCjwOj7 from Daniel Thiele @NicoleLaGruta1 @AngelaSciences @TabiHussain from @MonashBDI @Monash_FMNHS #mdpiijms via @IJMS_MDPI https://t.co/LWSBK3uCD6
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  • Paul G Thomas
    @PGTimmune
    2 months ago
    Fascinating difference in human and mouse innate recognition https://t.co/GHS6sVvsXD
    Veit Hornung
    @v_hornung
    2 months ago
    Adding to the recent NLRP1 inflammasome frenzy 🔥, we here report that NLRP1 functions as a sensor for double-stranded RNA @ScienceMagazine. Huge congrats to Stefan @sbauernfried who spearheaded this project ... https://t.co/DWafnf8DwK
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    Human NLRP1 is a sensor for double-stranded RNA

    Inflammasomes function as intracellular sensors of pathogen infection or cellular perturbation and thereby play a central role in numerous diseases. Given the high abundance of NLRP1 in epithelial...

    science.sciencemag.org
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  • Paul G Thomas
    @PGTimmune
    2 months ago
    ADAMTS1! https://t.co/IJEk3QFKJ6
    ATS G&G Section
    @ATS_GG
    2 months ago
    Integrative genomic analysis in African American children with asthma finds three novel loci associated with lung function https://t.co/UR6GyQgTVR
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    Integrative genomic analysis in African American children with asthma finds three novel loci...

    Bronchodilator (BD) drugs are commonly prescribed for treatment and management of obstructive lung function present with diseases such as asthma. Administration of BD medication can partially or...

    pubmed.ncbi.nlm.nih.gov
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  • St. Jude Research
    @StJudeResearch
    2 months ago
    Congratulations to Dr. Charles Rock, St. Jude Protein Production Facility director, named a #AAASfellow by @aaas for cutting-edge research on bacterial lipid metabolism which has advanced the promise of fatty acid synthesis inhibitors as new bacterial antibiotics. https://t.co/mnx3ZWQUtG
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  • Dennis Kyle
    @parasite_doc
    2 months ago
    Congratulations to Rick Tarleton for election as Fellow of AAAS! He was recognized for outstanding contributions to tropical medicine, especially for his studies of Chagas Disease. Well deserved Rick! @CTEGD @UGAResearch
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  • jordan
    @jordan_stratton
    2 months ago
    You won’t take a vaccine because you don’t know what’s in it? Real quick, name all the ingredients in a Pop Tart
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  • Dr. Marion Pepper
    @PepperMarion
    2 months ago
    It’s out! 🎉🎉🎉 https://t.co/xf1bdvIEKg
    Cell
    @CellCellPress
    2 months ago
    New Article now online: Functional SARS-CoV-2-specific immune memory persists after mild COVID-19 https://t.co/cU6cnMZxOg
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    Functional SARS-CoV-2-Specific Immune Memory Persists after Mild COVID-19

    Longitudinal analysis of immune memory following mild COVID-19 elicits memory lymphocytes that persist and display functional hallmarks of antiviral immunity.

    www.cell.com
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  • Nicholas A. Christakis
    @NAChristakis
    2 months ago
    The value of owning more books than you can read. I agree 100% with ⁦@nntaleb⁩ about this. And I wish my library were larger. :-) https://t.co/aKNEb7BeYi
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    The value of owning more books than you can read

    Or, how I learned to stop worrying and love my tsundoku.

    bigthink.com
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